I am running the Nitto Graplers on 18 x 10 rims with no lift, but my tires are only the 325/65R/18 and they do rub when turning sharply. I haven't found it to be a big problem, more of an annoyance. The tires are great though. I just took it on a 2500 mile road trip and the ride was smooth, and road noise was extremely low given the tire size.
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