Depending on how hard you want to rock...
I am not very experienced with the factory 05 touch screen nav, or any of the factory decks that come with the h2, so someone else will have to help you there.
If you can get an RCA out, or if it has an RCA out then it is really easy to attach and amplifier. Just deck -> amp then from amp -> speakers.
I haven't looked closely but the factory Bose speakers appear to be 5.25" in the front with 1" tweeters. The ones in the far rear may be 6.5" but once again I haven't really looked closely. My advice would be to go with JL Audio, you can get a nice Stealth Sub enclosure that wouldn't compromise appearance or your cargo space.
The stealthbox looks like this:
And installed...
And once again depending on how loud you want to go, you could go with one amp or two. I prefer to have an amp for subs (mono channel) and one for my mids-highs. A good sub amp would be the JL Audio 250/1
LINK TO 250/1 Specs
Likewise, the JL Audio Evolution XR would be a straight in replacement for the H2 Bose speakers. All sizes are available in them and they come with crossovers so you can cut off lowered frequencies to get rid of distortion.
LINK TO JL AUDIO EVOLUTION XR SERIES
I hope all of this information helps, I wish I could do more but without knowing what you want soundwise thats just some general ideas.
I would also recommend a 450/4 for your mids/highs. Anyhow hope this helps somewhat
